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Osmolar gap

Serum osmolar (osmolal) gap

Screens for an unmeasured osmole such as a toxic alcohol. Measured osmolality minus calculated (2 x Na + urea + glucose); a gap above about 10 is raised.

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Appears in these tutorials

See this calculator worked on a real patient, then read the teaching around it.

  • Poisoning and drug overdose11_026
    Worked example: Jarrod Douglas, 46
  • Metabolic acidosis15_101
    Worked example: Goran Horvat, 46
Celsus MedEd - Decoding the Matrix of Medicine